منابع مشابه
Increased Natural Killer Cells Activity in Schizophrenic Patients
Background: Schizophrenia has been associated with altered immunity. Different studies regarding natural killer cell activity (NKA) in schizophrenic patients have shown inconsistent results. Objectives: To evaluate NK cell activity in schizophrenic patients in comparison with healthy control individuals. Methods: 30 medication-free schizophrenic patients and 41 healthy sex, age and smoking st...
متن کاملErythrocyte: Bacteria killer and bacteria pray
Erythrocyte is human blood main bactericidal cell. During movement in blood stream erythrocytes are triboelectrically charged by rubbing to each other and vessel walls and this charge automatically attracts and keeps bacteria on erythrocyte surface. Bacteria fixation on erythrocyte membrane activates the receptors of the membrane and stimulates trans membrane releasing of oxygen from oxyhemoglo...
متن کاملComparison of Two Flow Cytometric Methods for Detection of Human Invariant Natural Killer T Cells (iNKT)
Background: Invariant natural killer cells (iNKT) are an important immunoregulatory T cell subset. Currently several flow cytometry-based approaches exist for the identifi-cation of iNKT cells, which rely on using the 6B11 monoclonal antibody or a combina-tion of anti-Vα24 and anti-Vβ11 antibodies. Objective: The aim of this study was to compare the ability of two flow cytometry-based methods f...
متن کاملNatural killer cells
What do they do? NK cells are equipped with cytotoxic granules that contain the arsenal of cytotoxic molecules used in killing virally infected and cancerous cells. They recognize their targets, in part, by means of activating signals that are only just beginning to be identified, but also by detecting cells that are deficient in cell-surface class I molecules of the major histocompatibility co...
متن کاملn Natural Killer Cells
The Src homology (SH) 2/SH3 domain-containing protein Grb2 and the oncoprotein Shc have been implicated in a highly conserved mechanism that regulates p21 ras activation. We investigated the involvement of these adaptor proteins in the signaling pathway induced by CD16 or interleukin (IL) 2R triggering in human natural killer (NK) cells. Both p46 and p52 forms of Shc were rapidly and transientl...
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ژورنال
عنوان ژورنال: Science
سال: 2011
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.333.6051.1803-b